Bisphenol A (BPA) in food contact materials - new scientific opinion from EFSA regarding public health risk.
نویسنده
چکیده
The wide use of bisphenol A (BPA) as a monomer in plastics manufacture or epoxy resins intended for food contact materials (FCM) has triggered numerous concerns due to toxicological findings indicating possible endocrine disrupting properties. This article traces the evolution of the scientific opinions since 1986 when the Tolerable Daily Intake (TDI) for BPA and its specific migration limit (SML) from plastic FCM into food were proposed for the first time by the Scientific Committee for Food (SCF). Resent extensive scientific studies concerning refined data on toxicity and exposure to BPA from food and non-food sources (eg. dust, cosmetics, thermal paper), including the most vulnerable groups of population, allowed the European Food Safety Authority (EFSA) to reduce the TDI of BPA from previously 50 µg/kg bw/day to now 4 µg/kg bw/day. EFSA's latest scientific opinion published in 2015 concludes that basing on the current estimations of total exposure to BPA from dietary and non-dietary sources for infants, children and adolescents is below the temporary TDI of 4 μg/kg bw/day. EFSA has also underlined that BPA poses no health risk at the estimated exposure levels of any population age group, including unborn children and the elderly. However, EFSA has indicated that some data on exposure and toxicological effects still require clarifications.
منابع مشابه
Breast Cancer UK response to the Draft Scientific Opinion on the risks to public health related to the presence of bisphenol A (BPA) in foodstuffs – Part: exposure assessment
On the 25th July, the European Food Safety Authority (EFSA) launched an open consultation on a draft assessment of consumer exposure to BPA performed by the EFSA’s Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (CEF Panel). This was the Authority’s first review of exposure to BPA since 2006 and the first to cover both dietary and non-dietary sources. Data from scienti...
متن کاملNo health risk for consumers from Bisphenol A exposure - the BfR endorses the conclusion of the new EFSA assessment - BfR communication No. 005/2015, 19 February 2015
In January 2015, the European Food Safety Authority (EFSA) published a new opinion on the assessment of the health risks associated with Bisphenol A (BPA) in foods and from other, non-dietary sources. In this opinion, the EFSA experts conclude that based on the current scientific evidence and given the current levels of consumer exposure, BPA does not pose a health risk for any age group. This ...
متن کاملQuantitative Assessment of Bisphenol A in Multiple Brands of Bottled Drinking Water in Iran
Background: Bisphenol A (BPA) is one of the hazardous materials causing disruption of endocrine pathways. Due to water contamination by this component from multiple sources and the associated health problems, BPA has been the focus of multiple studies. It has been proved that BPA may cause harm because of its impact on estrogenic receptors in human and other organisms. Methods: In this study, ...
متن کاملBiomonitoring Studies Should Be Used by Regulatory Agencies to Assess Human Exposure Levels and Safety of Bisphenol A
BACKGROUND Within the past 3 years, four major evaluations of bisphenol A (BPA) safety have been undertaken. However, these assessments have arrived at quite different conclusions regarding the safety of BPA at current human exposure levels. OBJECTIVES We compared the reasons provided by the European Food Safety Authority (EFSA) BPA risk assessment panel for their conclusion that human exposu...
متن کاملToxicokinetics of Bisphenol A Scientific Opinion of the Panel on Food additives, Flavourings, Processing aids and Materials in Contact with Food (AFC)
The Panel has been asked to reconsider the possible age-dependent toxicokinetics of BPA in animals and humans and their implication for hazard and risk assessment of BPA in food. The Panel concluded that the exposure of a human fetus to free BPA would be negligible due to the maternal capacity for conjugation whereas the fetal rat would be exposed to free BPA from the maternal circulation. Taki...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- Roczniki Panstwowego Zakladu Higieny
دوره 66 4 شماره
صفحات -
تاریخ انتشار 2015